3-(4-Amino-phenyl)-propyl]-carbamic acid tert-butyl ester
Carbamic acid, [3-(4-aminophenyl)propyl]-, 1,1-dimethylethyl ester
CAS: 180147-82-4
Molecular Formula: C14H22N2O2
3-(4-Amino-phenyl)-propyl]-carbamic acid tert-butyl ester - Names and Identifiers
3-(4-Amino-phenyl)-propyl]-carbamic acid tert-butyl ester - Physico-chemical Properties
| Molecular Formula | C14H22N2O2 |
| Molar Mass | 250.34 |
| Density | 1.061±0.06 g/cm3(Predicted) |
| Boling Point | 408.1±28.0 °C(Predicted) |
| pKa | 12.89±0.46(Predicted) |
| Storage Condition | 2-8 ℃, dark |
3-(4-Amino-phenyl)-propyl]-carbamic acid tert-butyl ester - Introduction
Carbamic acid, [3-(4-aminophenyl)propyl]-, 1,1-dimethylethyl ester is an organic compound whose Properties, Uses, preparation methods and safety information are as follows:
Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C16H23N3O2
-Molecular weight: 297.37g/mol
-Melting Point: about 110-115 degrees Celsius
-Solubility: better solubility in some organic solvents, such as dimethyl sulfoxide, dichloromethane, etc.
Use:
- Carbamic acid, [3-(4-aminophenyl)propyl]-, 1,1-dimethylethyl ester is an important organic synthesis intermediate, commonly used in drug synthesis and organic synthesis reactions. It can be used as a drug synthesis intermediate for the synthesis of various active drug molecules, such as anti-cancer drugs, antiviral drugs, anti-inflammatory drugs, etc.
-In addition, it can also be used for amino protecting groups in organic synthesis, and corresponding amino compounds can be obtained by deprotecting groups.
Method:
The preparation of-Carbamic acid, [3-(4-aminophenyl)propyl]-, 1,1-dimethylethyl ester is usually carried out by the following steps:
1. At low temperature, aniline is reacted with aminopropyl bromide to obtain 3-aminopropyl aniline.
2. The reaction of 3-aminopropylaniline with tetrabutyl chloroformate, the ester group of tetrabutyl chloroformate is removed under alkaline conditions to obtain Carbamic acid, [3-(4-aminophenyl)propyl]-, 1, 1-dimenthylethyl ester.
Safety Information:
- Carbamic acid, [3-(4-aminophenyl)propyl]-, 1,1-dimethylethyl ester is a chemical and should be handled in accordance with safe operating procedures.
-It may be irritating and corrosive to the eyes, skin and respiratory tract. Please be careful to avoid contact.
-in use to maintain good ventilation, avoid inhalation of harmful gases.
-Use personal protective equipment, such as chemical protective glasses, protective gloves and protective masks.
-When storing, keep it in a dry, cool place, avoid direct sunlight and high temperature conditions.
Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C16H23N3O2
-Molecular weight: 297.37g/mol
-Melting Point: about 110-115 degrees Celsius
-Solubility: better solubility in some organic solvents, such as dimethyl sulfoxide, dichloromethane, etc.
Use:
- Carbamic acid, [3-(4-aminophenyl)propyl]-, 1,1-dimethylethyl ester is an important organic synthesis intermediate, commonly used in drug synthesis and organic synthesis reactions. It can be used as a drug synthesis intermediate for the synthesis of various active drug molecules, such as anti-cancer drugs, antiviral drugs, anti-inflammatory drugs, etc.
-In addition, it can also be used for amino protecting groups in organic synthesis, and corresponding amino compounds can be obtained by deprotecting groups.
Method:
The preparation of-Carbamic acid, [3-(4-aminophenyl)propyl]-, 1,1-dimethylethyl ester is usually carried out by the following steps:
1. At low temperature, aniline is reacted with aminopropyl bromide to obtain 3-aminopropyl aniline.
2. The reaction of 3-aminopropylaniline with tetrabutyl chloroformate, the ester group of tetrabutyl chloroformate is removed under alkaline conditions to obtain Carbamic acid, [3-(4-aminophenyl)propyl]-, 1, 1-dimenthylethyl ester.
Safety Information:
- Carbamic acid, [3-(4-aminophenyl)propyl]-, 1,1-dimethylethyl ester is a chemical and should be handled in accordance with safe operating procedures.
-It may be irritating and corrosive to the eyes, skin and respiratory tract. Please be careful to avoid contact.
-in use to maintain good ventilation, avoid inhalation of harmful gases.
-Use personal protective equipment, such as chemical protective glasses, protective gloves and protective masks.
-When storing, keep it in a dry, cool place, avoid direct sunlight and high temperature conditions.
Last Update：2024-04-09 20:52:54
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Product Name: 4-(3-Boc-aMinopropyl)aniline Visit Supplier Webpage Request for quotation
CAS: 180147-82-4
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CAS: 180147-82-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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View History
3-(4-Amino-phenyl)-propyl]-carbamic acid tert-butyl ester
2-Naphthalenecarbonyl azide
METHYL 4-[(PHENOXYCARBONYL)OXY]BENZOATE
169038-53-3
142474-52-0
Diethyl chlrothiophosphate
3-甲氧基苯甲醛
2-FLUOROPYRIDINE-5-BORONIC ACID
Methyl 3-Hydroxy-5-trifluoromethyl-2-thiophenecarboxylate
赖氨酸二盐酸盐
2-Naphthalenecarbonyl azide
METHYL 4-[(PHENOXYCARBONYL)OXY]BENZOATE
169038-53-3
142474-52-0
Diethyl chlrothiophosphate
3-甲氧基苯甲醛
2-FLUOROPYRIDINE-5-BORONIC ACID
Methyl 3-Hydroxy-5-trifluoromethyl-2-thiophenecarboxylate
赖氨酸二盐酸盐